OBJECTIVES: The aim of this study was to describe the clinical, biological, and radiological characteristics and aetiological diagnosis of very late first inflammatory demyelinating events of the central nervous system.

CONCLUSIONS: This study highlights a particular phenotype of first clinical inflammatory demyelinating events in predominantly female patients aged >70 years who have severe motor impairment with common longitudinal extensive myelitis and large and common very active radiological inflammatory lesions. Neuromyelitis optica spectrum disorders seem overrepresented.

Authors
Lavandier N1, Bonnan M2, Carra-Dallière C3, Charif M3, Labauge P3, Camdessanche JP4, Edan G5, Naudin A6, Brassat D6, Ciron J7, Clavelou P8, Dulau C9, Moroso A9, Brochet B9, Ouallet JC10; on behalf Société Francophone de la Sclérose en Plaques (SFSEP).

Lien vers la publication : https://doi.org/10.1016/j.msard.2018.12.016